GMP Manufacturing

Cell banking

Pilot-scale manufacturing

Commercial manufacturing

TOT BIOPHARM has established a commercial GMP production base for biological drugs, which is equipped with a series of cell bank production lines (independent workshops) and several independent drug substance production lines. We provide MCB/WCB production and antibody DS manufacturing services in various scales, from 200 L to 2,000 L, with total capacity >20,000 L.

– TOT BIOPHARM uses production equipment of international leading brand, including Cytiva’s single use bioreactors and chromatography systems, as well as Millipore and PALL’s ultrafiltration systems.

– With single use technology and highly flexible production strategy, stages for batches and specifications at the same time can be accommodated.

– With extensive experience, the team has completed dozens of drug substance production, including the successful completion of multiple batches of marketed products.